Development of dual-targeted nano-dandelion based on an oligomeric hyaluronic acid polymer targeting tumor-associated macrophages for combination therapy of non-small cell lung cancer

• Glavni autori: Bingjie Wang (Autor), Wei Zhang (Autor), Xiudi Zhou (Autor), Mengna Liu (Autor), Xiaoya Hou (Autor), Ziting Cheng (Autor), Daquan Chen (Autor)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

In this study, the novel carrier materials were screened to structure targeting nano-micelles (named 'nano-dandelion') for synchronous delivery of curcumin (Cur) and baicalin (Bai), which could effectively overcome the tumor resistance. Mannose (Man) was found to bind better to CD206 recep...