The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma

• Main Authors: Maria S. Fedorova (Author), George S. Krasnov (Author), Elena N. Lukyanova (Author), Andrew R. Zaretsky (Author), Alexey A. Dmitriev (Author), Nataliya V. Melnikova (Author), Alexey A. Moskalev (Author), Sergey L. Kharitonov (Author), Elena A. Pudova (Author), Zulfiya G. Guvatova (Author), Anastasiya A. Kobelyatskaya (Author), Irina A. Ishina (Author), Elena N. Slavnova (Author), Anastasia V. Lipatova (Author), Maria A. Chernichenko (Author), Dmitry V. Sidorov (Author), Anatoly Y. Popov (Author), Marina V. Kiseleva (Author), Andrey D. Kaprin (Author), Anastasiya V. Snezhkina (Author), Anna V. Kudryavtseva (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background CpG island methylator phenotype (CIMP) is found in 15-20% of malignant colorectal tumors and is characterized by strong CpG hypermethylation over the genome. The molecular mechanisms of this phenomenon are not still fully understood. The development of CIMP is followed by global...