Immunogenicity of influenza vaccine in elderly people: a systematic review and meta-analysis of randomized controlled trials, and its association with real-world effectiveness

• Main Authors: Ziyan Meng (Author), Jiayou Zhang (Author), Jinrong Shi (Author), Wei Zhao (Author), Xiaoyuan Huang (Author), Li Cheng (Author), Xiaoming Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Older people (≥60 years old) are particularly vulnerable to influenza virus infection, and vaccine is effective in reducing the disease burden in this population. However, it remains obscure whether their antibody response is lower than those of younger adults (18-60 years old). Thus, th...