Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa

• Үндсэн зохиолчид: Nontokozo D. Matume (Зохиогч), Denis M. Tebit (Зохиогч), Laurie R. Gray (Зохиогч), Stephen D. Turner (Зохиогч), David Rekosh (Зохиогч), Pascal O. Bessong (Зохиогч), Marie-Louise Hammarskjöld (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2019-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) genes A3D, A3F, A3G and A3H have all been implicated in the restriction of human immunodeficiency virus type 1 (HIV-1) replication. Polymorphisms in these genes are likely to impact viral replication...