Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa

• Main Authors: Nontokozo D. Matume (Author), Denis M. Tebit (Author), Laurie R. Gray (Author), Stephen D. Turner (Author), David Rekosh (Author), Pascal O. Bessong (Author), Marie-Louise Hammarskjöld (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) genes A3D, A3F, A3G and A3H have all been implicated in the restriction of human immunodeficiency virus type 1 (HIV-1) replication. Polymorphisms in these genes are likely to impact viral replication...