Somatic targeted mutation profiling of colorectal cancer precursor lesions

• Main Authors: Wellington dos Santos (Author), Mariana Bisarro dos Reis (Author), Jun Porto (Author), Ana Carolina de Carvalho (Author), Marcus Matsushita (Author), Gabriela Oliveira (Author), Kari Syrjänen (Author), Rui Manuel Reis (Author), Denise Peixoto Guimarães (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Most colorectal cancers (CRC) arise from precursor lesions. This study aimed to characterize the mutation profile of colorectal cancer precursor lesions in a Brazilian population. Methods In total, 90 formalin-fixed paraffin-embedded colorectal precursor lesions, including 67 ade...