P-Rex1 Cooperates With TGFβR2 to Drive Lung Fibroblast Migration in Pulmonary Fibrosis

• Prif Awduron: Qing Liang (Awdur), Yanhua Chang (Awdur), Jing Liu (Awdur), Yan Yu (Awdur), Wancheng Qiu (Awdur), Jiajia Li (Awdur), Xu Yang (Awdur), Guangchun Sun (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Pulmonary fibrosis is a kind of interstitial lung disease with progressive pulmonary scar formation, leading to irreversible loss of lung functions. The TGF-β1/Smad signaling pathway plays a key role in fibrogenic processes. It is associated with the increased synthesis of extracellular matrix, enha...