Compound C Reducing Interferon Expression by Inhibiting cGAMP Accumulation
Cyclic GMP-AMP (cGAMP) synthase (cGAS) is a major DNA sensor responsible for cytosolic DNA-mediated innate immune response. Inhibition of cGAS may be an effective strategy for treating autoimmune diseases such as Aicardi-Goutieres syndrome and systemic lupus erythematosus. Compound C (also known as...
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Main Authors: | Junzhong Lai (Author), Xuan Luo (Author), Shuoran Tian (Author), Xing Zhang (Author), Shanlu Huang (Author), Hanze Wang (Author), Qiumei Li (Author), Shaoli Cai (Author), Qi Chen (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2020-02-01T00:00:00Z.
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