Repositioning of Lansoprazole as a Protective Agent Against Cisplatin-Induced Ototoxicity
Cisplatin (CDDP) is a well-known chemotherapeutic drug approved for various cancers. However, CDDP accumulates in the inner ear cochlea via organic cation transporter 2 (OCT2) and causes ototoxicity, which is a major clinical limitation. Since lansoprazole (LPZ), a proton pump inhibitor, is known to...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-07-01T00:00:00Z.
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