A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice
Activation of T cells specific for insulin B chain amino acids 9 to 23 (B:9-23) is essential for the initiation of type 1 diabetes (T1D) in non-obese diabetic mice. We previously reported that peptide/MHC complexes containing optimized B:9-23 mimotopes can activate most insulin-reactive pathogenic T...
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Materyal Türü: | Kitap |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |