Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data

• Main Authors: Veronika A. Myasoedova (Author), Sara Rega (Author), Vincenza Valerio (Author), Donato Moschetta (Author), Ilaria Massaiu (Author), Giorgia Bonalumi (Author), Giampiero Esposito (Author), Valentina Rusconi (Author), Francesca Bertolini (Author), Gianluca Lorenzo Perrucci (Author), Paolo Poggio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AimsThoracic aortic aneurysm (TAA) that progress to acute aortic dissection is often fatal and there is no pharmacological treatment that can reduce TAA progression. We aim to evaluate statins' effects on TAA growth rate and outcomes using a meta-analysis approach.Methods and resultsA detailed...