Tackling Stereochemistry in Drug Molecules with Vibrational Optical Activity

• Main Authors: Jonathan Bogaerts (Author), Roy Aerts (Author), Tom Vermeyen (Author), Christian Johannessen (Author), Wouter Herrebout (Author), Joao M. Batista (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chirality plays a crucial role in drug discovery and development. As a result, a significant number of commercially available drugs are structurally dissymmetric and enantiomerically pure. The determination of the exact 3D structure of drug candidates is, consequently, of paramount importance for th...