Off-label and unlicensed drug treatments in Neonatal Intensive Care Units: a systematic review

• Main Authors: Fábio Reis (Author), Rita Pissarra (Author), Henrique Soares (Author), Paulo Soares (Author), Hercília Guimarães (Author)
• Format: Book
• Published: Hygeia Press di Corridori Marinella, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Newborns are particularly susceptible to off-label and unlicensed (OLUL) drug treatments, especially in the intensive care setting, inferring from dosing regimens and indications supported in older populations and built on non-neonatal pathophysiology. This use leads to unpredictable drug effectiven...