NOX4 Mediates <i>Pseudomonas aeruginosa</i>-Induced Nuclear Reactive Oxygen Species Generation and Chromatin Remodeling in Lung Epithelium

• Main Authors: Panfeng Fu (Author), Ramaswamy Ramchandran (Author), Tara Sudhadevi (Author), Prasanth P. K. Kumar (Author), Yashaswin Krishnan (Author), Yuru Liu (Author), Yutong Zhao (Author), Narasimham L. Parinandi (Author), Anantha Harijith (Author), Junichi Sadoshima (Author), Viswanathan Natarajan (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Pseudomonas aeruginosa</i> (<i>PA</i>) infection increases reactive oxygen species (ROS), and earlier, we have shown a role for NADPH oxidase-derived ROS in <i>PA</i>-mediated lung inflammation and injury. Here, we show a role for the lung epithelial cell (LEpC...