Bulk Flow Optimisation of Amorphous Solid Dispersion Excipient Powders through Surface Modification

• Главные авторы: Danni Suhaidi (Автор), Yao-Da Dong (Автор), Paul Wynne (Автор), Karen P. Hapgood (Автор), David A. V. Morton (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-05-01T00:00:00Z.
• Предметы: article
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Particulate amorphous solid dispersions (ASDs) have been recognised for their potential to enhance the performance of various solid dose forms, especially oral bioavailability and macromolecule stability. However, the inherent nature of spray-dried ASDs leads to their surface cohesion/adhesion, incl...