Combination of the PARPi and ARSi in advanced castration resistant prostate cancer: a review of the recent phase III trials
Tumors with an impaired ability to repair DNA double-strand breaks by homologous recombination, including those with alterations in breast cancer 1 and 2 (BRCA1 and BRCA2) genes, are very sensitive to blocking DNA single-strand repair by inhibition of the poly (ADP-ribose) polymerase (PARP) enzyme....
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Open Exploration Publishing Inc.,
2024-08-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |