α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles

• Main Authors: Juliano Machado (Author), Wilian A. Silveira (Author), Dawit A. Gonçalves (Author), Aline Zanatta Schavinski (Author), Muzamil M. Khan (Author), Neusa M. Zanon (Author), Mauricio Berriel Diaz (Author), Rüdiger Rudolf (Author), Isis C. Kettelhut (Author), Luiz C. Navegantes (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Although it is well established that a-calcitonin gene-related peptide (CGRP) stabilizes muscle-type cholinergic receptors nicotinic subunits (AChR), the underlying mechanism by which this neuropeptide regulates muscle protein metabolism and neuromuscular junction (NMJ) morphology is uncl...