Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain Regions

• Main Authors: Kenta Kobayashi (Author), Ken-ichi Inoue (Author), Soshi Tanabe (Author), Shigeki Kato (Author), Masahiko Takada (Author), Kazuto Kobayashi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gene transfer through retrograde axonal transport of viral vectors offers a substantial advantage for analyzing roles of specific neuronal pathways or cell types forming complex neural networks. This genetic approach may also be useful in gene therapy trials by enabling delivery of transgenes into a...