Parishin C Attenuates Phencyclidine-Induced Schizophrenia-Like Psychosis in Mice: Involvements of 5-HT1A Receptor

• Main Authors: Eun-Joo Shin (Author), Wan Kyunn Whang (Author), Sungun Kim (Author), Jae-Hyung Bach (Author), Jin-Man Kim (Author), Xuan-Khanh Thi Nguyen (Author), Thuy-Ty Lan Nguyen (Author), Bae Dong Jung (Author), Kiyofumi Yamada (Author), Toshitaka Nabeshima (Author), Hyoung-Chun Kim (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parishin C, a major component of Gastrodia elata BLUME (GE), was purified from GE. Because GE modulates the serotonergic system and the 5-HT1A receptor is an important therapeutic target of schizophrenia, we examined whether parishin C affects phencyclidine-induced abnormal behaviors in mice. Phency...