Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle

• Main Authors: Chu-Sook Kim (Author), Yeonsoo Joe (Author), Hye-Seon Choi (Author), Sung Hoon Back (Author), Jeong Woo Park (Author), Hun Taeg Chung (Author), Eun Roh (Author), Min-Seon Kim (Author), Tae Youl Ha (Author), Rina Yu (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Obesity-induced skeletal muscle inflammation is a major contributor of skeletal muscle loss/atrophy and is implicated in metabolic complications such as insulin resistance. Fibroblast growth factor 21 (FGF21) is known to be an important metabolic regulator with anti-inflammatory...