Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy
Pim-1 kinase, a serine/threonine kinase, is often overexpressed in various cancers, contributing to disease progression and poor prognosis. In this study, we explored the potential of flavonoids as inhibitors of Pim-1 kinase using a combination of molecular docking and steered molecular dynamics (SM...
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Main Authors: | Hani A. Alhadrami (Author), Ahmed M. Sayed (Author), Hossam M. Hassan (Author), Albaraa H. Alhadrami (Author), Mostafa E. Rateb (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2024-10-01T00:00:00Z.
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