Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2

• Main Authors: Shuping Li (Author), Yunpeng Zhang (Author), Gang Deng (Author), Yuwen Wang (Author), Shenglan Qi (Author), Xuemei Cheng (Author), Yueming Ma (Author), Yan Xie (Author), Changhong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Harmaline and harmine occur naturally in plants and are distributed endogenously in human and animal tissues. The two β-carboline alkaloids possess potential for treating Alzheimer's disease, Parkinson's disease, depression and other central nervous system diseases. However, studies have s...