SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease

• Asıl Yazarlar: Rishi S. Mehta (Yazar), Zachary L. Taylor (Yazar), Lisa J. Martin (Yazar), Michael J. Rosen (Yazar), Laura B. Ramsey (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2022-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Low‐dose methotrexate (MTX) is an immunosuppressant used to treat inflammatory bowel disease (IBD). SLCO1B1 genetic variation has been associated with delayed MTX clearance and increased toxicity. The purpose of this study was to evaluate the association between SLCO1B1 genetic variation an...