Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes.

• Main Authors: Tsung-Ting Tsai (Author), Yi-Jui Chuang (Author), Yee-Shin Lin (Author), Chih-Peng Chang (Author), Shu-Wen Wan (Author), Sheng-Hsiang Lin (Author), Chia-Ling Chen (Author), Chiou-Feng Lin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin (IL)-10 levels are increased in dengue virus (DENV)-infected patients with severe disorders. A hypothetical intrinsic pathway has been proposed for the IL-10 response during antibody-dependent enhancement (ADE) of DENV infection; however, the mechanisms of IL-10 regulation remain unclear...