Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution

• Main Authors: Tamada Yasushi (Author), Taichi Misako (Author), Nishiuchi Yuji (Author), Minaba Masaomi (Author), Ueno Satoshi (Author), Yamazaki Toshimasa (Author), Kato Yusuke (Author)
• Format: Book
• Published: BMC, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Cationic antimicrobial peptides (CAMPs) are well recognized to be promising as novel antimicrobial and antitumor agents. To obtain novel skeletons of CAMPs, we propose a simple strategy using acid-amide substitution (i.e. Glu→Gln, As...