Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

The comparative performances of physiologically‐based pharmacokinetic (PBPK) modeling and allometric scaling for predicting the pharmacokinetics (PKs) of large molecules in pediatrics are unknown. Therefore, both methods were evaluated for accuracy in translating knowledge of infliximab PKs from adu...

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Autores principales: Paul R. V. Malik (Autor), Andrea N. Edginton (Autor)
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Publicado: Wiley, 2019-11-01T00:00:00Z.
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Número de Clasificación: A1234.567
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