Discoidin Domain Receptors: Potential Actors and Targets in Cancer

• Main Authors: Hassan eRammal (Author), Charles eSaby (Author), Kevin eMagnien (Author), Laurence eVan Gulick (Author), Roselyne eGarnotel (Author), Emilie eBuache (Author), Hassan eEl Btaouri (Author), Pierre eJeannesson (Author), Hamid eMorjani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The extracellular matrix critically controls cancer cell behavior by inducing several signaling pathways through cell membrane receptors. Besides conferring structural properties to tissues around the tumor, the extracellular matrix is able to regulate cell proliferation, survival, migration and inv...