Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast
Point mutations in the human MYO1E gene, encoding class I myosin Myo1e, are associated with focal segmental glomerulosclerosis (FSGS), a primary kidney disorder that leads to end-stage kidney disease. In this study, we used a simple model organism, fission yeast Schizosaccharomyces pombe, to test th...
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Main Authors: | Jing Bi (Author), Robert T. Carroll (Author), Michael L. James (Author), Jessica L. Ouderkirk (Author), Mira Krendel (Author), Vladimir Sirotkin (Author) |
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Format: | Book |
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The Company of Biologists,
2015-08-01T00:00:00Z.
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