Parent-Metabolite Pharmacokinetic Modeling of Formononetin and Its Active Metabolites in Rats after Oral Administration of Formononetin Formulations

• Main Authors: Ju Hee Kim (Author), Dong Wook Kang (Author), Seok-jin Cho (Author), Hea-Young Cho (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2022-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Formononetin is a major isoflavone contained in propolis and is reported to exhibit various pharmacological effects. However, the use of formononetin in pharmaceutical industry is limited due to its low bioavailability and solubility. There had been several efforts on formononetin formulation develo...