Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments
Hypoxia and oncogene expression both stimulate glycolytic metabolism in tumors, thereby leading to lactate production. However, lactate is more than merely a by-product of glycolysis: it can be used as a metabolic fuel by oxidative cancer cells. This phenomenon resembles processes that have been des...
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Format: | Book |
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The Company of Biologists,
2011-11-01T00:00:00Z.
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A1234.567 |
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