Ts-Hsp70 induces protective immunity against Trichinella spiralis infection in mouse by activating dendritic cells through TLR2 and TLR4.

• Main Authors: Rui Zhang (Author), Qing Sun (Author), Yi Chen (Author), Ximeng Sun (Author), Yuan Gu (Author), Zhang Zhao (Author), Yuli Cheng (Author), Limei Zhao (Author), Jingjing Huang (Author), Bin Zhan (Author), Xinping Zhu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trichinellosis is a serious food-borne parasitic zoonosis worldwide. In the effort to develop vaccine against Trichinella infection, we have identified Trichinella spiralis Heat shock protein 70 (Ts-Hsp70) elicits partial protective immunity against T. spiralis infection via activating dendritic cel...