AIM2 Inflammasome Activation Leads to IL-1α and TGF-β Release From Exacerbated Chronic Obstructive Pulmonary Disease-Derived Peripheral Blood Mononuclear Cells

• Main Authors: Chiara Colarusso (Author), Michela Terlizzi (Author), Antonio Molino (Author), Pasquale Imitazione (Author), Pasquale Somma (Author), Roberto Rega (Author), Antonello Saccomanno (Author), Rita P. Aquino (Author), Aldo Pinto (Author), Rosalinda Sorrentino (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic obstructive pulmonary disease (COPD) is now the fourth-leading cause of death worldwide and its prevalence is increasing. The progressive decline of lung function and airway remodelling are a consequence of chronic inflammatory responses. It was recently postulated the involvement of the inf...