Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals

• প্রধান লেখক: Jingjing Ma (লেখক), Yinxian Yang (লেখক), Yinghua Sun (লেখক), Jin Sun (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2017-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Azilsartan (AZL), a poorly soluble drug, was considered to be fit for nanocrystals to improve its solubility. Our study intended to prepare AZL nanocrystals by means of bead milling method. Eight stabilizers or their binary combination and the milling time were set to be variable factors to optimize...