Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals

• Asıl Yazarlar: Jingjing Ma (Yazar), Yinxian Yang (Yazar), Yinghua Sun (Yazar), Jin Sun (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2017-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Azilsartan (AZL), a poorly soluble drug, was considered to be fit for nanocrystals to improve its solubility. Our study intended to prepare AZL nanocrystals by means of bead milling method. Eight stabilizers or their binary combination and the milling time were set to be variable factors to optimize...