Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair

• Main Authors: Thanushiyan Poobalasingam (Author), Laura L. Yates (Author), Simone A. Walker (Author), Miguel Pereira (Author), Nina Y. Gross (Author), Akmol Ali (Author), Maria Kolatsi-Joannou (Author), Marjo-Riitta Jarvelin (Author), Juha Pekkanen (Author), Eugenia Papakrivopoulou (Author), David A. Long (Author), Mark Griffiths (Author), Darcy Wagner (Author), Melanie Königshoff (Author), Matthew Hind (Author), Cosetta Minelli (Author), Clare M. Lloyd (Author), Charlotte H. Dean (Author)
• Format: Book
• Published: The Company of Biologists, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung diseases impose a huge economic and health burden worldwide. A key aspect of several adult lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), including emphysema, is aberrant tissue repair, which leads to an accumulation of damage and im...