Ribosome biogenesis and degradation regulate translational capacity during muscle disuse and reloading

• Main Authors: Vandré C. Figueiredo (Author), Randall F. D'Souza (Author), Douglas W. Van Pelt (Author), Marcus M. Lawrence (Author), Nina Zeng (Author), James F. Markworth (Author), Sally D. Poppitt (Author), Benjamin F. Miller (Author), Cameron J. Mitchell (Author), John J. McCarthy (Author), Esther E. Dupont‐Versteegden (Author), David Cameron‐Smith (Author)
• Format: Book
• Published: Wiley, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Translational capacity (i.e. ribosomal mass) is a key determinant of protein synthesis and has been associated with skeletal muscle hypertrophy. The role of translational capacity in muscle atrophy and regrowth from disuse is largely unknown. Therefore, we investigated the effect...