Long interspersed nuclear element 1 hypomethylation has novel prognostic value and potential utility in liquid biopsy for oral cavity cancer

• Main Authors: Kiyoshi Misawa (Author), Satoshi Yamada (Author), Masato Mima (Author), Takuya Nakagawa (Author), Tomoya Kurokawa (Author), Atsushi Imai (Author), Daiki Mochizuki (Author), Daichi Shinmura (Author), Taiki Yamada (Author), Junya Kita (Author), Ryuji Ishikawa (Author), Yuki Yamaguchi (Author), Yuki Misawa (Author), Takeharu Kanazawa (Author), Hideya Kawasaki (Author), Hiroyuki Mineta (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background New biomarkers are urgently needed to improve personalized treatment approaches for head and neck squamous cell carcinoma (HNSCC). Global DNA hypomethylation has wide-ranging functions in multistep carcinogenesis, and the hypomethylation of long interspersed nucleotide element-1...