Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma

• Main Authors: Zhaoming Lu (Author), Yandan Ren (Author), Li Yang (Author), Ang Jia (Author), Yi Hu (Author), Yu Zhao (Author), Wuduo Zhao (Author), Bin Yu (Author), Wen Zhao (Author), Jianying Zhang (Author), Guiqin Hou (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sulforaphane (SFN), a natural anti-tumor compound from cruciferous vegetables, has been reported to induce protective autophagy to cancer cells, which might impair the anti-tumor efficiency of SFN. However, the accurate function and mechanism of SFN inducing autophagy in cancers are still obscure, e...