Cerebrospinal Fluid Concentrations of Meropenem and Vancomycin in Ventriculitis Patients Obtained by TDM-Guided Continuous Infusion

• मुख्य लेखकों: Christoph Tiede (लेखक), Ute Chiriac (लेखक), Daniel Dubinski (लेखक), Florian J. Raimann (लेखक), Otto R. Frey (लेखक), Anka C. Röhr (लेखक), Anna Wieduwilt (लेखक), Michael Eibach (लेखक), Natalie Filmann (लेखक), Christian Senft (लेखक), Kai Zacharowski (लेखक), Volker Seifert (लेखक), Jan Mersmann (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Effective antibiotic therapy of cerebral infections such as meningitis or ventriculitis is hindered by low penetration into the cerebrospinal fluid (CSF). Because continuous infusion of meropenem and vancomycin and routine therapeutic drug monitoring (TDM) have been proposed to optimize antimicrobia...