Biological Effects in Cancer Cells of Mono- and Bidentate Conjugation of Cisplatin on PAMAM Dendrimers: A Comparative Study

• मुख्य लेखकों: Cláudia Camacho (लेखक), Dina Maciel (लेखक), Helena Tomás (लेखक), João Rodrigues (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cisplatin (<i>cis</i>-diamminedichloroplatinum(II)) is a potent chemotherapeutic agent commonly used to treat cancer. However, its use also leads to serious side effects, such as nephrotoxicity, ototoxicity, and cardiotoxicity, which limit the dose that can be safely administered to pati...