Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage-Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production
Obesity is an important risk factor for osteoarthritis (OA) in weight-bearing joints, but also in hand joints, pointing to an obesity-related metabolic factor that influences on the pathogenesis of OA. Leptin is an adipokine regulating energy balance, and it has recently been related also to arthrit...
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| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Βιβλίο |
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Hindawi Limited,
2009-01-01T00:00:00Z.
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