Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a major health burden in need for new medication. To identify potential drug targets a genomic study was performed in lipid-laden primary human hepatocyte (PHH) and human hepatoma cell cultures. Methods PHH, HuH7 and HepG2 hepatoma cel...

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Main Authors: Stephanie Breher-Esch (Author), Nishika Sahini (Author), Anna Trincone (Author), Christin Wallstab (Author), Jürgen Borlak (Author)
Format: Book
Published: BMC, 2018-12-01T00:00:00Z.
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3rd Floor Main Library

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