Aaptamine - a dual acetyl - and butyrylcholinesterase inhibitor as potential anti-Alzheimer's disease agent

• Main Authors: Shuang Miao (Author), Qianqian He (Author), Chen Li (Author), Yan Wu (Author), Mengshan Liu (Author), Yongshou Chen (Author), Shizhou Qi (Author), Kaikai Gong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people worldwide. Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) are promising therapeutic targets for AD.Objective To evaluate the inhibitory effects of aaptamine on two cholinesterases and...