Maternal and fetal factors influencing fetal fraction: A retrospective analysis of 153,306 pregnant women undergoing noninvasive prenatal screening

• Main Authors: Cechuan Deng (Author), Jianlong Liu (Author), Sha Liu (Author), Hongqian Liu (Author), Ting Bai (Author), Xiaosha Jing (Author), Tianyu Xia (Author), Yunyun Liu (Author), Jing Cheng (Author), Xiang Wei (Author), Lingling Xing (Author), Yuan Luo (Author), Quanfang Zhou (Author), Qian Zhu (Author), Shanling Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundGenetic factors are important causes of birth defects. Noninvasive prenatal screening (NIPS) is widely used for prenatal screening of trisomy 21, trisomy 18, and trisomy 13, which are the three most common fetal aneuploidies. Fetal fraction refers to the proportion of cell-free fetal DNA i...