Meningococcal factor H binding proteins in epidemic strains from Africa: implications for vaccine development.

• Main Authors: Rolando Pajon (Author), Andrew M Fergus (Author), Oliver Koeberling (Author), Dominique A Caugant (Author), Dan M Granoff (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Factor H binding protein (fHbp) is an important antigen for vaccines against meningococcal serogroup B disease. The protein binds human factor H (fH), which enables the bacteria to resist serum bactericidal activity. Little is known about the vaccine-potential of fHbp for control of meningococcal ep...