Isopropyl Gallate, a Gallic Acid Derivative: In Silico and In Vitro Investigation of Its Effects on <i>Leishmania major</i>

• Main Authors: Danielly Silva de Melo (Author), José Arimatéa de Oliveira Nery Neto (Author), Maisa de Sousa dos Santos (Author), Vinícius Duarte Pimentel (Author), Rita de Cássia Viana Carvalho (Author), Valéria Carlos de Sousa (Author), Ruy Gabriel Costa Sousa (Author), Lázaro Gomes do Nascimento (Author), Michel Muálem de Moraes Alves (Author), Daniel Dias Rufino Arcanjo (Author), Damião Pergentino de Sousa (Author), Fernando Aécio de Amorim Carvalho (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Isopropyl gallate (IPG) is a polyphenol obtained from alterations in the gallic acid molecule via acid catalysis with previously reported leishmanicidal and trypanocidal activities. The present study aims to evaluate in silico binding activity towards some targets for antileishmanial chemotherapy ag...