An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing

An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing

BackgroundIn the context of the cytokine storm the takes place in severe COVID-19 patients, the Interleukin 6 (IL6) pathway emerges as one of the key pathways involved in the pathogenesis of this hyperinflammatory state. The strategy of blocking the inflammatory storm by targeting the IL6 is a promi...

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Main Authors: Alejandro Durán-Sotuela (Author), Jorge Vázquez-García (Author), Sara Relaño-Fernández (Author), Vanesa Balboa-Barreiro (Author), Juan Fernández-Tajes (Author), Francisco J. Blanco (Author), Ignacio Rego-Pérez (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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