The dynamics of immunoglobulin V-gene usage and clonotype expansion in mice after prime and boost immunizations as analyzed by NGS

In the current study, an improved NGS approach was developed to study the B-cell repertoire evolution in a simple mouse immunization model including only two DNA immunizations. The combination of 5'RACE and Ion Torrent long reads enabled unbiased immunoglobulin repertoire analysis even from sma...

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Main Authors: Diego J. Farfán-Arribas (Author), Shuying Liu (Author), Shixia Wang (Author), Shan Lu (Author)
Format: Book
Published: Taylor & Francis Group, 2017-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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