Hyaluronic acid-ibuprofen conjugation: a novel ototherapeutic approach protecting inner ear cells from inflammation-mediated damage

• Main Authors: Bhaskar Birru (Author), Joachim G. S. Veit (Author), Elizabeth M. Arrigali (Author), Jack Van Tine (Author), Emma Barrett-Catton (Author), Zachary Tonnerre (Author), Philippe Diaz (Author), Monica A. Serban (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

There is a substantial need of effective drugs for the treatment of hearing loss, which affects nearly 500 million individuals globally. Hearing loss can be the result of intense or prolonged noise exposure, ototoxic drugs, infections, and trauma, which trigger inflammatory signaling cascades that l...