The therapeutic potential of Apigenin in amyotrophic lateral sclerosis through ALDH1A2/Nrf2/ARE signaling

• Main Authors: Huiting Liang (Author), Xinhui Zhou (Author), Jie Zhang (Author), Wenyuan Xu (Author), Yi Liu (Author), Xinxin Wang (Author), Yushu Hu (Author), Renshi Xu (Author), Xiaobing Li (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by motor neuron loss leading to muscle weakness and atrophy. Apigenin (APG), known for its antioxidant properties, holds potential as a therapeutic compound in ALS. Methods We used the Tg...