Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway

• Autores principales: Jianping Ma (Autor), Miao Zheng (Autor), Xinyue Zhang (Autor), Jiaqi Lu (Autor), Lili Gu (Autor)
• Formato: Libro
• Publicado: BMC, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Alzheimer's disease (AD) is the most prevalent neurodegenerative and remains incurable. Aluminum is a potent neurotoxin associated with AD. The main pathological features of AD are extracellular amyloid-β protein deposition and intracellular hyperphosphorylated Tau protein....